Thesis - Development of an evaluation matrix for a modular on-demand production

Fraunhofer-Gesellschaft

ThesisGerman needed: fluent

Still open on 1 Nov

You apply on the company's own website.

What you'll do

You will develop a uniform evaluation matrix taking into account space framework conditions (e.g., number of media changes, degree of process automation, maturity level of sub-processes in the space context such as microfluidics or bioreactors), thereby separating common core operations from product-specific special operations.
You will conduct a gap analysis that identifies existing technological, infrastructural, and regulatory gaps between current terrestrial ATMP production and a potential application in space, and derive recommendations for action on which technologies/competencies are missing in Europe.
Knowledge Base Report in English.

You are studying biotechnology, bioprocess engineering, pharmaceutical engineering, medical engineering, process engineering, or a comparable degree program at a university/higher education institution in Germany/within Europe.
You are interested in cell and gene therapies (ATMPs) and their manufacturing processes.
You work in a structured, analytical, and independent manner and enjoy interdisciplinary, forward-looking questions.
You have a good command of German and English.
Ideally, you have initial knowledge in the analysis and evaluation of processes.

Insights into the project work of an interdisciplinary research team in cooperation with the European Space Agency (ESA).
An exciting, forward-looking question at the interface of biopharmaceuticals, production technology, and space medicine.
Intensive supervision by our team.
Insights into a modern research environment at the Fraunhofer Institute for Manufacturing Engineering and Automation IPA, Department of Pharmaceutical and Bioproduction Technology.
The opportunity to contribute to a highly innovative topic and integrate your results into ongoing research activities.
Flexible arrangement of working hours and workplace.

You will develop a uniform evaluation matrix taking into account space framework conditions (e.g., number of media changes, degree of process automation, maturity level of sub-processes in the space context such as microfluidics or bioreactors), thereby separating common core operations from product-specific special operations.
You will conduct a gap analysis that identifies existing technological, infrastructural, and regulatory gaps between current terrestrial ATMP production and a potential application in space, and derive recommendations for action on which technologies/competencies are missing in Europe.
Knowledge Base Report in English.

You are studying biotechnology, bioprocess engineering, pharmaceutical engineering, medical engineering, process engineering, or a comparable degree program at a university/higher education institution in Germany/within Europe.
You are interested in cell and gene therapies (ATMPs) and their manufacturing processes.
You work in a structured, analytical, and independent manner and enjoy interdisciplinary, forward-looking questions.
You have a good command of German and English.
Ideally, you have initial knowledge in the analysis and evaluation of processes.

Insights into the project work of an interdisciplinary research team in cooperation with the European Space Agency (ESA).
An exciting, forward-looking question at the interface of biopharmaceuticals, production technology, and space medicine.
Intensive supervision by our team.
Insights into a modern research environment at the Fraunhofer Institute for Manufacturing Engineering and Automation IPA, Department of Pharmaceutical and Bioproduction Technology.
The opportunity to contribute to a highly innovative topic and integrate your results into ongoing research activities.
Flexible arrangement of working hours and workplace.